Topic: Har1

Fenton compares ancient genetic modifications to modern CRISPR and gene drive technologies. He points to "Human Accelerated Regions" (HARs) in the genome, particularly those affecting brain development and the neocortex, as evidence of targeted engineering rather than random mutation.

Analysis of the HAR1 DNA segment shows only two changes between chickens and chimpanzees over 300 million years, but 18 changes between chimpanzees and humans in just 6 million years. Fenton argues the statistical probability of this occurring naturally is zero, indicating deliberate modification of the human brain.